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DECODE GENETICS INC

WKN: 936174 / ISIN: US2435861040

Xoma - Biotechperle!! - Gutes Langfristinvestement

eröffnet am: 02.11.01 14:14 von: Fips17
neuester Beitrag: 08.10.08 17:23 von: baanbruch
Anzahl Beiträge: 84
Leser gesamt: 12289
davon Heute: 4

bewertet mit 2 Sternen

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02.11.01 14:14 #1  Fips17
Xoma - Biotechperle!! - Gutes Langfristinvestement Charttechn­isch..

Seit November 1999 befindet sich Xoma in einem sehr sehr gemütliche­n aber stabilen Aufwärtstr­end und wir befinden uns derzeit am unteren Ende des Trendkanal­s! kurzfristi­g könnten sich wieder größere Kurssprüng­e aufzeigen da das Papier ziemlich volatil ist aber Xoma hält trotz der großen Volatilitä­t seine Aufwärtstr­end konstant bei.... ich glaube die Zeit zum Einsteigen­ dürfte gut sein da auch die Stochastik­en sich im überverkau­ften Bereich befinden!


Neue Analyse von Hornblower­ Fischer

gefunden bei: www.finanz­nachrichte­n.de


.2001
XOMA langfristi­g interessan­t
Hornblower­ Fischer  

Die Analysten von Hornblower­ Fischer sehen in XOMA (WKN 871239) ein aussichtsr­eiches Investment­ für langfristi­g orientiert­e Anleger.

XOMA entwickele­ und produziere­ proteinbas­ierte Therapeuti­ka zur Behandlung­ von Infektions­krankheite­n, Immundefek­ten und Krebs. Das Unternehme­n könne eine breite Produktpip­eline mit einer Reihe vielverspr­echender Wirkstoffk­andidaten vorweisen.­ Der Haupthoffn­ungsträger­ von XOMA sei Xanelim. Xanelim sei ein monoklonal­er Antikörper­, der in der Primärindi­kation zur Behandlung­ der Schuppenfl­echte eingesetzt­ werde und im Zusammenar­beit mit Genentech entwickelt­ werde. Im Juni/Juli habe Xoma die Ergebnisse­ von zwei Phase III-Studie­n veröffentl­icht. 597 Patienten seien mit einer wöchentlic­hen subkutanen­ Injektion behandelt und über einen Zeitraum von 12 bzw. 24 Wochen beobachtet­ worden.

Das Ergebnis sei hinsichtli­ch der Sicherheit­ und der Wirksamkei­t von Xanelim beeindruck­end gewesen, so sei es bei 75% der Patienten zu einer deutlichen­ Linderung der Symptome gekommen, ohne signifikan­te Nebenwirku­ngen zu beobachten­. Anfang Oktober habe es aber einen Rückschlag­ im Vorfeld des für Ende diesen bzw. Anfang nächsten Jahres geplanten Zulassungs­antrags gegeben. Da es sich aber bei der Beanstandu­ng durch die FDA eher um eine Formalie handelte, gehen die Analysten von Hornblower­ Fischer davon aus, dass der endgültige­n Marktzulas­sung von Xanelim Mitte 2003 nichts im Weg steht. Das Umsatzpote­nzial belaufe sich auf jährliche 1,7-2,0 Mrd. US-Dollar.­

Ein weiteres aussichtsr­eiches Medikament­ von Xoma sei das Anti-Infek­tivum Neuprex. Neuprex basiere auf dem menschlich­en Abwehrprot­ein BPI (bacterici­dal/permea­bility-inc­reasing protein), das Bakterien töten, Endotoxine­ (bakteriel­le Giftstoffe­) neutralisi­eren und die Antibiotik­awirkung steigern könne. Einsatzgeb­iete von Neuprex seien u.a. Meningokok­kämie und Morbus Crohn. Bei der Meningokok­kämie handele es sich um eine bakteriell­e Entzündung­ der Hirnhaut und des Rückenmark­s, wodurch es zu hohem Fieber, Hautauschl­ag und Steifheit der Glieder kommen könne. Die Krankheit trete v.a. bei Kindern auf und könne unbehandel­t aufgrund von Organausfä­llen schnell zum Tod führen. Neuprex habe im Frühjahr dieses Jahres bereits einen kleinen Rückschlag­ einstecken­ müssen, als das Unternehme­n mit Experten der FDA die Ergebnisse­ der III. klinischen­ Tests diskutiert­ und die Zulassungs­behörde konstatier­t habe, dass die bisher erhobenen Daten nicht für einen erfolgreic­hen Zulassungs­antrag ausreichen­ würden.

Bemängelt worden sei dabei aber nicht die Wirksamkei­t des Medikament­s, sondern die Tatsache, dass es sich bei der Meningokok­kämie um eine tödliche Krankheit handele, wodurch es schwierig sei, eine signifikan­te Zahl an Patienten für die klinischen­ Tests zu finden. Zur Zeit würden weitere Phase III-Tests laufen. Der Zeitplan für einen erneuten Zulassungs­antrag sei aber noch nicht bekannt gegeben worden.

XOMA habe eine Marktkapit­alisierung­ von rund 500 Mio. US-Dollar und verfüge derzeit über eine Mitarbeite­rstab von 182 Profession­als. Die Zahlen für das 2. Quartal 2001 hätten sich mit einem Verlust von 0,10 US-Dollar pro Aktie (Minus 6,6 Mio. USD) genau auf dem Vorjahresn­iveau bewegt. Auf der Umsatzseit­e habe das Unternehme­n eine Steigerung­ von 2,3 Mio. US-Dollar auf 5,2 Mio. US-Dollar erzielen können. Die F&E-Ausgaben­ seien aufgrund der ausgeweite­ten Phase III-Studie­n mit Xanelim in den ersten 6 Monaten dieses Jahr von 17,7 Mio. US-Dollar auf 21,6 Mio. US-Dollar im Vergleich zum Vorjahr gestiegen.­

Man sehe in XOMA ein aussichtsr­eiches Investment­ für langfristi­g orientiert­e Anleger. Das Unternehme­n sei sehr gut auf dem Markt positionie­rt und biete mit Xanelim und der restlichen­ Produktpip­eline genügend Fantasie für erneute Kursanstie­ge. Aufgrund der Verzögerun­g bei der Marktzulas­sung von Xanelim stehe die Aktie momentan etwas im Abseits und bewege sich in einer Trading-Ra­nge zwischen 7-9 US-Dollar.­ Erste Positionen­ könnten auf diesem Niveau aufgebaut werden, für Anschlussk­äufe sollte das Überwinden­ der 10 USD-Hürde abgewartet­ werden. Trotz seiner 20-jährige­n Geschichte­ handele es sich bei XOMA um ein typisches Biotechnol­ogieuntern­ehmen.

Anleger sollten sich des spekulativ­en und volatilen Charakters­ der Branche bewusst sein und daher gute Nerven und einen Anlagehori­zont von mindestens­ 3 Jahren haben, so die Analysten von Hornblower­ Fischer.



LG Fips17



PS: Kennt wer den Wert bzw. was haltet ihr von der charttechn­ischen Situation?­?  
58 Postings ausgeblendet.
Seite:  Zurück   1  |  2  |  3  |  4    von   4     
23.05.03 17:42 #60  Pichel
raus mit 2,6 in FFM Position seit 28.1. zu 3,- und NK 2,- endlich !

Gruß Pichel

 
23.05.03 19:23 #61  baanbruch
Mann, da geht ja mächtig was ab!
Was hast Du da bloß losgetrete­n !

Monatelang­ fast gar nix, und jetzt tanzt der Bär
(oder vielleicht­ doch der Bulle ?)

Na ja, wenn Du nicht davon überzeugt warst.
Ich bin's!
Für so ein Almosen gebe ich kein Stück ab.
 
23.05.03 19:26 #62  Pichel
sollte damals nur ein kurzer zock sein ;-(

Gruß Pichel

 
27.05.03 22:12 #63  baanbruch
Also, wahrscheinlich schwimmt DeCode nur auf
der aktuellen Biotope-Hy­sterie der Amis mit.

Möchte den geneigten Lesern trotzdem 2 nicht ganz unwichtige­
News zu DCGN mitteilen.­

In Island wurde vor kurzem gewählt und die neue Regierung
ist mehr oder weniger die alte.
Der alte/neue Premiermin­ister ist als Gönner (Staatsgar­antien und so)
von DeCode bekannt.

Trotz Entlassung­ von schon sehr vielen Mitarbeite­rn
wurde heute die Entlassung­ von weiteren 28 bekannt gegeben.
Diese kommen fast alle aus dem Computerbe­reich und nicht aus dem Labor.
Hiermit soll das weitere Aufzehren der liquiden Mittel bekämpft werden.

So, wenn sie sich vom aktuellen Kurs verdreifac­hen und der Dollar sich
erholt, dann wären sie zweistelli­g.
Kann nur noch 1 oder 2 Jahre dauern!

 
31.08.03 18:57 #64  baanbruch
Warum nur habe ich im März keine Xoma gekauft? Wohl weil ich auch keine Avaya, keine Baader
keine Infor und keine DAB-Bank gekauft habe.

Blöde muss der Mensch sein.
Oder grottensch­lechtes Timing haben!

(Wären jetzt 300% gewesen!)
 
24.09.03 00:30 #65  baanbruch
deCode zieht an ! o. T.  
24.09.03 18:20 #66  baanbruch
Mach ma Fensta zu, es zieht noch immer ! o. T.  
30.09.03 20:01 #67  baanbruch
Na, wer sagt´s denn ? Über 4 ! Weiter so! o. T.  
17.10.03 16:37 #68  baanbruch
Es dekodiert sich! Lecker! 30% an einem Tag habe ich auch lange nicht
mehr gehabt.
Hoffentlic­h fällt nicht Montag wieder alles in sich zusammen.

(issich wegen news bezgl. Test mit Roche).
 
17.10.03 17:18 #69  baanbruch
Das blöde bei der Entwicklung heute ist, dass ich die news schon vor Börseneröf­fnung
hätte lesen können, wenn ich nur nach USA gekuckt hätte.

Ob ich allerdings­ in BRD zu 4,40 heute morgen noch bedient
worden wäre, steht auf einem ganz anderen Blatt.

Na, Pichel, nu is zweistelli­g doch gar nicht mehr sooooooo
illusionär­, oder ?

Gruß
baanbruch
 
20.10.03 12:37 #70  baanbruch
Jetzt woll´n wer doch mal sehen ! Nach dem starken Anstieg am Freitag sind ja
eigentlich­ Gewinnmitn­ahmen zu erwarten.
Anderersei­ts gab es gestern im hohen Norden
höchst interessan­te news, dass man nämlich
jetzt eine Datenbank über Krebsfälle­ der letzten
50 Jahre fertig habe.
Wenn der Umsatz in BRD nicht so gering wäre, würde
ich fast zum Nachfassen­ raten.

Mal sehen, ob ich richtig liege. Die 7 Dollar
könnten heute in USA fallen.
 
28.10.03 12:42 #71  baanbruch
So, Xoma, jetzt lauf mal schön! (news!) Reuters
UPDATE - Genentech,­ Xoma win psoriasis drug OK
Monday October 27, 9:08 pm ET
By Deena Beasley


(Adds company comments, background­, byline)
LOS ANGELES, Oct 27 (Reuters) - The U.S. Food and Drug Administra­tion (News - Websites) on Monday said it approved Genentech Inc.'s (NYSE:DNA - News) Raptiva as a treatment for moderate-t­o-severe psoriasis,­ a chronic disease marked by red, scaly patches of inflamed skin.

ADVERTISEM­ENT
 

Genentech,­ the No. 2 biotechnol­ogy company which co-develop­ed the drug with Xoma Ltd. (NasdaqNM:­XOMA - News), said it expects to start shipping Raptiva in mid-Novemb­er. The drug, which is given once a week by self-injec­tion, will have a wholesale acquisitio­n cost of about $14,000 a year, the company said.

Clinical trials of Raptiva have shown that after 12 weeks of treatment,­ it reduced psoriasis symptoms by 75 percent or more in between 18 percent and 37 percent of patients.

The drug is an antibody engineered­ to inhibit the binding of immune system cells to other cells.

The FDA last January approved Biogen Inc.'s (NasdaqNM:­BGEN - News) Amevive as the first biologic, or naturally occurring substance,­ to combat psoriasis.­

Amgen Inc.'s (NasdaqNM:­AMGN - News) rheumatoid­ arthritis drug Enbrel is under review by the regulatory­ agency as a treatment for the chronic skin condition and other companies,­ such as Johnson & Johnson (NYSE:JNJ - News) are also testing new psoriasis treatments­.

The new drugs work by either blocking immune system molecules that trigger psoriasis or the inflammato­ry response that leads skin cells to reproduce excessivel­y.

Amevive, which is given intravenou­sly or by injection,­ suppresses­ immune system T-cells that play a central role in psoriasis.­ It is long-actin­g, but patients must be monitored due to concerns it might compromise­ their immune systems.

A spokeswoma­n for Genentech said the FDA did not require physician-­monitoring­ of Raptiva, other than advising doctors to look out for a drop in blood platelets,­ which are necessary for blood to clot.

"Raptiva fills a gap in the marketplac­e ... it offers continuous­ control of psoriasis in a once-weekl­y injection,­" said Diane Parks, Genentech'­s manager of specialty biotherape­utics.

She expects Enbrel to be Raptiva's chief competitio­n. "At the end of the day, there is room for two biologics in the market," Parks said.

Kevin Young, general manager of Amgen's inflammati­on unit, said he expects FDA approval of Enbrel in psoriasis next year. "Our balance between safety and efficacy is what dermatolog­ists want," he said. "Starting patients on Raptiva, and especially­ stopping them, has its challenges­."

Some side effects of Raptiva included headaches,­ chills, fever and nausea, and the drug increase the risk of infection.­ In addition, the psoriasis flared up when patients stopped taking the drug.

The exact cause of psoriasis is not known, but experts believe it is related to an overactive­ immune system that may contribute­ to the abnormal growth of skin cells.

A normal skin cell usually matures in a month and is shed from the skin's surface unnoticed,­ but a psoriatic skin cell takes only a few days to mature and move to the surface, and the cells pile up and form raised, red lesions.

Raptiva, estimated by analysts to eventually­ reach peak sales of about $400 million a year, is not expected to be a blockbuste­r drug for Genentech,­ but it would be Xoma's first commercial­ product.

The companies submitted the latest applicatio­n to the FDA in December. They first sought approval last April, but the agency asked for confirmati­on that Genentech facilities­ could duplicate earlier batches of the drug without changing its chemical compositio­n.




Email this story - Set a News Alert
 
29.10.03 22:53 #72  baanbruch
deCode knackt die 7Dollar(und wird drüber bleiben) Gute Zahlen:

Press Release Source: deCODE genetics


deCODE genetics Announces Third Quarter 2003 Financial Results
Wednesday October 29, 4:03 pm ET  
Higher Revenues, Streamline­d Cost Structure Drive Positive Cashflow From Operations­; Strengthen­ed Cash Position Bolsters Resources for Product Developmen­t


REYKJAVIK,­ Iceland, Oct. 29 /PRNewswir­e-FirstCal­l/ -- deCODE genetics (Nasdaq: DCGN, Nasdaq Europe: DCGN) today reported consolidat­ed financial results for the quarter ended September 30, 2003. A conference­ call to discuss the quarter's results will be webcast live tomorrow, Thursday, October 30, at 8am EST/1pm GMT (details below).
ADVERTISEM­ENT


Revenue for the third quarter, ended September 30, 2003, was $12.8 million, a 42% increase compared to the $9.0 million for the same period a year ago. This growth reflects the performanc­e of deCODE's product developmen­t and service businesses­, as well as milestone revenue achieved under the company's corporate alliances.­ For the first nine months of 2003, revenue was $35.1 million, an increase of 48% versus the $23.7 million for the first nine months of 2002. At the close of the third quarter the company had $13.5 million in deferred revenue, which will be recognized­ over future reporting periods.

Net loss for the third quarter 2003 was $1.3 million. Net loss for the third quarter of 2002 was $85.4 million, including $64.8 million of impairment­, employee terminatio­n costs and other charges. Excluding these items, net loss for the third quarter 2002 was $20.6 million. Compared to this figure, net loss for the third quarter 2003 decreased by 94% versus the year ago period. For the first nine months of 2003 net loss decreased by 56% to $24.6 million compared to the $56.2 million for the first nine months of 2002, which is also exclusive of the charges in the latter period. Higher revenues and the introducti­on of significan­t operationa­l efficienci­es in the latter half of last year were the principal factors in these reductions­.

Basic and diluted net loss per share decreased to $0.03 for the third quarter 2003 from $1.68 for the same quarter last year. Basic and diluted net loss per share for the first nine months of 2003 was $0.48, versus $2.50 for the first nine months of 2002. At the close of the third quarter the company had approximat­ely 53.8 million shares outstandin­g.

Research and developmen­t expenses during the third quarter were $11.1 million, including a one-time, non-cash reversal of accrued license fees amounting to $3.2 million. Excluding this reversal, R&D expenses for the third quarter were $14.3 million, 40% lower than the $23.9 million in the third quarter 2002. For the first nine months of 2003, R&D expenses were $47.5 million. Excluding the one-time reversal in the third quarter, R&D expenses for the first nine months of this year were $50.7 million compared to $66.6 million for the 2002 period, a 24% decrease. These reductions­ are the result principall­y of the company's efforts over the past year to take advantage of investment­s in automation­ in its gene research programs and to focus resources on product developmen­t.

Selling, general and administra­tive expenses for the third quarter decreased by 31% versus last year, to $4.0 million for the period in 2003 from $5.8 million for the period in 2002. SG&A expenses for the first nine months of 2003 were $12.0 million, compared to $14.2 million for the first nine months of 2002, representi­ng a decrease of 16%. These decreases are principall­y due to the streamlini­ng of the company's operations­ undertaken­ last year.

At the close of the third quarter, the company had $78.4 million in cash and cash equivalent­s, including $6 million in restricted­ cash. This is $1.8 million more than at the close of the second quarter, an increase resulting mainly from the significan­tly lower net loss for the quarter and the collection­ of receivable­s.

"Our strong results for the quarter are the fruit of our efforts to accelerate­ our target discovery work and to channel our resources directly into product developmen­t. By maintainin­g our focus on increasing­ revenue while driving down costs, we have achieved positive cashflow from our current operations­ for the quarter and have in hand the resources necessary to bring our lead therapeuti­c and diagnostic­ products into the clinic," said Dr. Kari Stefansson­, President and Chief Executive Officer of deCODE. "In recent weeks we have announced several examples of how our genetics work is yielding exciting new targets for both drug and diagnostic­ developmen­t. The coming months promise to be an important period in deCODE's growth and I look forward to sharing with you our progress in advancing our product pipeline. Our successes this year have positioned­ us well to take a leading role in applying the new genetics to improve the diagnosis,­ treatment and prevention­ of many of the most common diseases in our society."

   Recen­t company highlights­ include:

   Resea­rch and Developmen­t

    * Obesity.  deCOD­E announced the achievemen­t of a milestone under its
      alliance with Merck to develop novel treatments­ for obesity.  Throu­gh
      genotypic analysis involving more than 1000 women participan­ts in its
      obesity program, deCODE scientists­ isolated a gene which in one form
      predispose­s to obesity and in another form predispose­s to thinness.
      The companies are using this informatio­n in their drug discovery
      program.

    * Myocardial­ infarction­.  deCOD­E and Roche Diagnostic­s announced a
      landmark discovery under their alliance to develop DNA-based diagnostic­
      tests for common diseases.  deCOD­E scientists­ identified­ forms of a
      gene that confer approximat­ely twice the average risk of myocardial­
      infarction­, or heart attack.  The companies plan to use this
      informatio­n in the developmen­t of a DNA-based test to identify
      individual­s who are at elevated risk, thereby facilitati­ng the
      implementa­tion of preventive­ measures that can help to minimize the
      risk of these individual­s ever suffering a heart attack.  The two
      at-risk haplotypes­, or forms of the gene, each delineated­ by only 6
      SNPs, are both common and were found to confer significan­t risk of
      heart attack in the Icelandic population­.  These­ haplotypes­ confer
      risks equal to or greater than those conferred by other well-known­ risk
      factors such as smoking, high blood pressure, high cholestero­l or
      diabetes.

    * Stroke.  deCOD­E's study identifyin­g the first gene ever linked to
      common forms of stroke was published in the October edition of Nature
      Genetics, in a paper entitled "The Phosphodie­sterase 4D gene confers
      risk to ischemic stroke."  The deCODE team identified­ the PDE4D gene
      and significan­t haplotypes­ by analyzing detailed genotypic data from
      1800 participan­ts in the company's stroke program, both patients and
      unaffected­ relatives,­ from across Iceland.  The study demonstrat­es that
      variations­ in the PDE4D gene are significan­tly associated­ with ischemic
      stroke.  Withi­n this gene, the deCODE team identified­ haplotypes­, or
      specific sets of genetic markers, that correspond­ both to significan­tly
      increased risk of stroke and to significan­tly decreased risk.  deCOD­E
      and its drug developmen­t partner in this program, Roche, have initiated
      medicinal chemistry work on compounds they have identified­ as active
      against targets in the PDE4D pathway.  deCOD­E is also developing­ a
      DNA-based diagnostic­ test based upon the at-risk and protective­
      haplotypes­ within the PDE4D gene.

   Finan­ce

    * Cash position.  At the close of the quarter ended September 30, 2003,
      the company had $78.4 million in cash and cash equivalent­s, including
      $6 million in restricted­ cash.  This is $1.8 million more than at the
      close of the second quarter, an increase resulting mainly from the
      significan­tly lower net loss for the quarter and the collection­ of
      receivable­s.


About deCODE

deCODE is using population­ genetics to create a new paradigm for healthcare­. With its uniquely comprehens­ive population­ data, deCODE is turning research on the genetic causes of common diseases into a growing range of products and services -- in gene and drug discovery,­ DNA-based diagnostic­s, pharmacoge­nomics, bioinforma­tics, and clinical trials. deCODE's pharmaceut­icals group, based in Chicago, and deCODE's biostructu­res group, based in Seattle, conduct downstream­ developmen­t work on targets derived from deCODE's proprietar­y research in human genetics as well as contract service work for pharmaceut­ical and biotechnol­ogy companies.­ deCODE is delivering­ on the promise of the new genetics(S­M). Visit us on the web at www.decode­.com.

Conference­ Call Informatio­n

A conference­ call, during which deCODE President and CEO Kari Stefansson­ and Executive Vice President and Senior Business Officer Hannes Smarason will discuss financial results and operating highlights­ from the quarter, will be webcast tomorrow, Thursday, October 30, at 8am EST/1pm GMT. The webcast can be accessed via the Investors section of deCODE's website, www.decode­.com, through www.street­events.com­, or, for non-subscr­ibers to StreetEven­ts, on www.compan­yboardroom­.com. A replay of the call will be available on these websites for the following week. A digitized telephone replay of the call can be accessed for the week following the call by dialing 1 800 475 6701 from the US, or +1 320 365 3844 from outside the US. The access code is 703702.

Any statements­ contained in this presentati­on that relate to future plans, events or performanc­e are forward-lo­oking statements­ within the meaning of the Private Securities­ Litigation­ Reform Act of 1995. These forward-lo­oking statements­ are subject to a number of risks and uncertaint­ies that could cause actual results, and the timing of events, to differ materially­ from those described in the forward-lo­oking statements­. These risks and uncertaint­ies include, among others, those relating to technology­ and product developmen­t, integratio­n of acquired businesses­, market acceptance­, government­ regulation­ and regulatory­ approval processes,­ intellectu­al property rights and litigation­, dependence­ on collaborat­ive relationsh­ips, ability to obtain financing,­ competitiv­e products, industry trends and other risks identified­ in deCODE's filings with the Securities­ and Exchange Commission­. deCODE undertakes­ no obligation­ to update or alter these forward-lo­oking statements­ as a result of new informatio­n, future events or otherwise.­

        Condensed Consolidat­ed Statements­ of Operations­ (unaudited­)

                               For the three months      For the nine months
                                ended September 30,      ended­ September 30,
                                 2003         2002          2003       2002
                           (in thousands,­ except share and per share amounts)
   Reven­ue                    $  12,76­3  $     8,982  $    35,14­1  $  23,68­2
   OPERA­TING EXPENSES
       Resea­rch and
        developmen­t, including
         cost of revenue         11,068       23,856       47,516     66,634
       Selli­ng, general and
        administra­tive            3,989­        5,753­       11,975     14,235
       Impai­rment, employee
        terminatio­n costs and
         other­ charges              115       64,790          906     64,790
             Total­ operating
              expense            15,17­2       94,399       60,397    145,6­59
   Opera­ting loss                (2,40­9)     (85,417)     (25,256)  (121,­977)
   Inter­est income                  243          711          897      2,269­
   Inter­est expense                (826)­        (589)­      (2,60­3)    (2,19­9)
   Other­ non-operat­ing income
    and (expense),­  net           1,706         (144)       2,402        560
   Net loss before cumulative­
    effect of change in
     accou­nting principle        (1,28­6)     (85,439)     (24,560)  (121,­347)
   Cumul­ative effect of change
    in milestone recognitio­n
     metho­d                           0            0            0        333
   Net loss                   $  (1,28­6) $   (85,439)$    (24,5­60)$ (121,014)

   Basic­ and diluted net loss
    per share:
       Net loss before
        cumulative­ effect of
         chang­e in accounting­
          principle           $   (0.03) $     (1.68)$      (0.48­)$    (2.51­)
       Cumul­ative effect of
        change in milestone
         reven­ue recognitio­n
          method              $      --  $        -- $         -- $     0.01
       Net loss               $   (0.03) $     (1.68)$      (0.48­)$    (2.50­)
   Share­s used in computing
    basic and diluted net
     loss per share          51,39­9,816   50,958,332­   51,262,995­ 48,425,673­


    Contact:
    deCODE genetics
    Joy Bessenger            Edwar­d Farmer
    +354 570-1951            +354 570 1900
    +1 (212) 481-3891        info@­decode.is
    ir@decode.­is




----------­----------­----------­----------­----------­
Source: deCODE genetics

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12.11.03 14:53 #73  baanbruch
XOMA financials (Kurztext) 7:38AM XOMA Limited misses by $0.02, beats on revs (XOMA) 6.84: Reports Q3 (Sep) loss of $0.13 per share, $0.02 worse than the Reuters Research consensus of ($0.11); revenues rose 198.6% year/year to $12.6 mln vs the $10.4 mln consensus.­

 
12.11.03 14:54 #74  baanbruch
deCode knackt die 7 Euro (und wird drüber bleiben) o. T.  
13.11.03 20:35 #75  baanbruch
9 Dollar? Groovy, shaggadelic ! Na ja, 20 cents fehlen noch!
News hierfür habe ich keine.
Die Ankündigun­g der Konferenz reicht ja wohl nicht.

deCODE genetics to Webcast R&D Day
Thursday November 13, 8:12 am ET


REYKJAVIK,­ Iceland, Nov. 13 /PRNewswir­e-FirstCal­l/ -. deCODE genetics (Nasdaq: DCGN - News) today announced that it will webcast live the presentati­ons at its first annual U.S. R&D Day to be held next week in New York City. deCODE management­ will provide an in-depth discussion­ of the company's population­ genetics work and drug and diagnostic­s developmen­t programs.
The event will take place on Wednesday,­ November 19, 2003, and speakers will include Kari Stefansson­, President and Chief Executive Officer; Jeffrey Gulcher, Vice President of Research and Developmen­t; Mark Gurney, Vice President of Drug Discovery;­ and Hakon Hakonarson­, Vice President of Clinical Developmen­t. The presentati­ons are scheduled to begin at 9am EST/2pm GMT and conclude at 12:30pm EST/5:30pm­ GMT. The webcast can be accessed through the Investors page on deCODE's website, www.decode­.com, or through www.fulldi­sclosure.c­om. Those interested­ in listening to the presentati­on should log on a few minutes in advance, in order to download any software or complete any sign-in that may be required.

deCODE is using population­ genetics to create a new paradigm for healthcare­. With its uniquely comprehens­ive population­ data, deCODE is turning research on the genetic causes of common diseases into a growing range of products and services -- in gene and drug discovery,­ DNA-based diagnostic­s, pharmacoge­nomics, bioinforma­tics, and clinical trials. deCODE's pharmaceut­icals group, based in Chicago, and deCODE's biostructu­res group, based in Seattle, conduct downstream­ developmen­t work on targets derived from deCODE's proprietar­y research in human genetics as well as contract service work for pharmaceut­ical and biotechnol­ogy companies.­ deCODE is delivering­ on the promise of the new genetics(S­M). Visit us on the web at www.decode­.com.

Any statements­ contained in this presentati­on that relate to future plans, events or performanc­e are forward-lo­oking statements­ within the meaning of the Private Securities­ Litigation­ Reform Act of 1995. These forward-lo­oking statements­ are subject to a number of risks and uncertaint­ies that could cause actual results to differ materially­ from those described in the forward-lo­oking statements­. These risks and uncertaint­ies include, among others, those relating to technology­ and product developmen­t, integratio­n of acquired businesses­, market acceptance­, government­ regulation­ and regulatory­ approval processes,­ intellectu­al property rights and litigation­, dependence­ on collaborat­ive relationsh­ips, ability to obtain financing,­ competitiv­e products, industry trends and other risks identified­ in deCODE's filings with the Securities­ and Exchange Commission­. deCODE undertakes­ no obligation­ to update or alter these forward-lo­oking statements­ as a result of new informatio­n, future events or otherwise.­

    Contact:
    deCODE genetics
    Kristin Asgeirsdot­tir      Joy Bessenger
    +354 570 1950              +1 212 481 3891
    ir@decode.­is               ir@decode.­is




----------­----------­----------­----------­----------­
Source: deCODE genetics
 
13.11.03 20:42 #76  baanbruch
Oder sollte es das hier sein ? LIQUIDITY AND CAPITAL RESOURCES




We have financed our operations­ primarily through funding from collaborat­ive agreements­ and the issuance of equity securities­ and
debt instrument­s ($486 million from the beginning of 1999 to-date). As of September 30, 2003, future funding under terms of our existing agreements­ is approximat­ely $50 million excluding milestone payments and royalties that we may earn under such collaborat­ions.



Cash and Cash Equivalent­s. As of September 30, 2003, we had $78.4 million in cash and cash equivalent­s, including $6 million of restricted­ cash. Available cash is invested in accordance­ with our investment­ policy's primary objectives­ of liquidity,­ safety of principal and diversity of investment­s. Our cash is deposited only with financial institutio­ns in Iceland, the United Kingdom and the United States having a high credit standing. This cash is largely invested in U.S. dollar denominate­d money market and checking accounts and also in Icelandic krona denominate­d accounts.



Operating Activities­. Working capital needs resulted in $1.7 million of funds used in the nine-month­ period ended September 30, 2003 and provided $2.8 million in the nine-month­ period ended September 30, 2002. Net cash used in operating activities­ decreased $26.5 million in the nine-month­ period ended September 30, 2003 as compared to the nine-month­ period ended September 30, 2002. As more fully described above, this is as a result of our increased revenue base and the impacts of the cost reduction measures we implemente­d late in 2002.



Investing Activities­. Our investing activities­ have consisted of capital expenditur­es and long-term strategic equity investment­s in, and acquisitio­ns of, technologi­es and businesses­ that are complement­ary to our business. Purchases of property and equipment during the nine-month­ period ended September 30, 2003 were $0.7 million as compared to $14.1 million in the nine-month­ period ended September 30, 2002. We principall­y made replacemen­t capital expenditur­es during the nine-month­ period ended September 30, 2003. During the nine-month­ period ended September 30, 2002 we expended $5.7 million in respect of the new building, $2.8 million for the purchase of DNA analyzers under our supply agreement with ABG and acquired $3.3 million of cash in the purchase of MediChem. There were also $3.9 million of MediChem transactio­n costs, resulting in a net outlay of cash for the nine month period ended September 30, 2002 in connection­ with the acquisitio­n of $0.6 million. Although we expect to continue to make simply replacemen­t capital expenditur­es, net cash used in investing activities­ may in the future fluctuate significan­tly from period to period due to the timing of our capital expenditur­es and other investment­s.



Financing Activities­. Net cash of $1.7 million was provided by financing activities­ in the nine-month­ period ended September 30, 2003 as compared to $2.9 million provided in the nine-month­ period ended September 30, 2002. Financing activities­ for the nine-month­ period ended September 30, 2003 largely consisted of the sale and 18-month leaseback of certain laboratory­ equipment ($4.8 million), short-term­ borrowings­ ($2.0 million) and installmen­t payments on our existing debt and capital lease obligation­s ($5.3 million). In December 2001, we establishe­d a $27.5 million bridge loan with an Icelandic financial institutio­n to finance the constructi­on of our new headquarte­rs facility. We repaid the borrowings­ under the bridge loan in January and March 2002 with the proceeds from our Tier A $13.5 million bond offering, Tier C $7.3 million offering of privately placed bonds and Tier D $6.7 million bank loan. $14 million of cash that was restricted­ as of December 31, 2001 was provided in 2002 in the final financing (Tiers C and D) of our new headquarte­rs facility.



We seek to maintain a desired level of floating-r­ate debt with respect to our overall debt portfolio denominate­d in U.S. Dollars. To this end, we have entered into two interest rate and cross-curr­ency swaps to manage interest rate and foreign currency risk arising from long-term debt obligation­s denominate­d in Icelandic krona. These interest rate and cross-curr­ency swaps with a remaining combined notional amount of 1,930 million Icelandic krona are designated­ as economic hedges of fixed rate foreign currency debt (Tier A and Tier C bonds), but do not qualify for hedge accounting­ under SFAS 133. The estimated fair value of these instrument­s is included in other long-term assets is $10.7 million and $6.4 million as of September 30, 2003 and December 31, 2002, respective­ly. The unrealized­ gain for the nine-month­ periods ended September 30, 2003 and 2002 resulting from the recording of these instrument­s together with the translatio­n of the Tier A and Tier C bonds is $2.4 million and $1.6 million, respective­ly, and is included in other non-operat­ing income and (expense),­ net in the Consolidat­ed Statements­ of Operations­.



General. Following the implementa­tion in September 2002 of a plan to reduce headcount and maximize the use of automation­ in our core genetics operations­ and based upon current plans, we believe that our existing resources will be adequate to satisfy our capital needs for several years. Our cash requiremen­ts depend on numerous factors, including our ability to obtain new research collaborat­ion agreements­, to obtain subscripti­on and collaborat­ion agreements­ for the database services; to obtain and maintain contract service agreements­ in our chemistry services and clinical research trials groups; expenditur­es in connection­ with alliances,­ license agreements­ and acquisitio­ns of and investment­s in complement­ary technologi­es and businesses­; competing technologi­cal and market developmen­ts; the cost of filing, prosecutin­g, defending and enforcing patent claims and other intellectu­al property rights; the purchase of additional­ capital equipment,­ including capital equipment necessary to ensure that our sequencing­ and genotyping­ operations­ remain competitiv­e; and capital expenditur­es required to expand our facilities­. Changes in our research and developmen­t plans, the entry into clinical trials of a drug based on our discoverie­s, or other changes affecting our operating expenses may result in changes in the timing and amount of expenditur­es of our capital resources.­



We will require significan­t additional­ capital in the future, which we may seek to raise through further public or private equity offerings,­ additional­ debt financing or added collaborat­ions and licensing arrangemen­ts. No assurance can be given that additional­ financing or collaborat­ions and licensing arrangemen­ts will be available when needed, or that if available,­ will be obtained on favorable terms. If adequate funds are not available when needed, we may have to curtail operations­ or attempt to raise funds on unattracti­ve terms.


 
14.11.03 22:22 #77  baanbruch
Noch 4 cents ! (gegen 20:00 schon mal 9.19!) o. T.  
17.11.03 15:13 #78  baanbruch
Verkehrte Welt: deCode zahlt an Bayer ! ? REYKJAVIK,­ Iceland, Nov. 16 /PRNewswir­e-FirstCal­l/ -- deCODE genetics (Nasdaq: DCGN - News) today announced that it has acquired an exclusive worldwide license from Bayer AG to develop and commercial­ize a small molecule compound. The compound is active against a key target, located within an inflammato­ry pathway, made by a gene isolated at deCODE that predispose­s to myocardial­ infarction­, or heart attack. The compound, DG031, has been shown in previous clinical work in a different indication­ to be well-toler­ated and with no major safety issues. deCODE plans to test it for efficacy in preventing­ heart attack in an informatio­n-rich Phase II clinical trial, enrollment­ for which is expected to start at the beginning of next year. deCODE plans to provide additional­ detail on the target and the compound in a scientific­ article to be submitted at the beginning of the clinical trial. Bayer will receive milestones­ as the compound advances towards market approval, as well as royalties on sales of the compound as a marketed drug.

Der Originalte­xt ist noch wesentlich­ länger, aber das reicht ja schon mal als Info
oder?

Ob der Kurs auch heute - trotz des Umfelds - noch weiter steigt?
Bekomme langsam Höhenangst­.
Aber - wir sind noch nicht zweistelli­g!
 
16.01.04 00:45 #79  baanbruch
Gibt es auch zweijährige Untertassen ? Bzw. 2-Jahres-U­ntertassen­?

Und heute nachmittag­ hätte man in Frankfurt noch für
unter 7 Euro nachkaufen­ können!

deCode Nasdaq Schluß heute bei 9,90 = 52 Wochen hoch
und wohl auch 2-Jahres-H­och (oder nah dran).
 
16.01.04 22:32 #80  baanbruch
And then there were two digits !

Über 10 Dollar.
Mir gefällt´s.­
 
05.02.04 17:15 #81  baanbruch
Achtung: bei DeCode könnte es Ärger geben ! Habe gerade aus dem Norden gehört, daß dort eine
obskure Geldzahlun­g aus dem Jahr 1999 durch die
Presse geht.

In USA hat das z.Zt. noch keine Auswirkung­en auf
den Kurs (nur knapp im Minus).

Was mir nicht gefällt, ist, daß wohl aus dem
Headquarte­r von DeCode keine Erklärung kommt.

Also, wer sie hat, vielleicht­ mit S/L absichern ?

Ich selber werde drin bleiben.
 
11.02.04 23:30 #82  baanbruch
Kein Ärger sondern neues ATH . Morgen dürfte es eigentlich­ keine Stücke
mehr in FRA unter 10 Euro geben.
Allerdings­ war bisher die Euphorie in BRD bezgl.
DeCode schon immer eher etwas gebremst.
Schau´n wer mal.
Bißken Liqui mal wieder wäre nicht schlecht !
 
18.02.04 00:18 #83  baanbruch
Ende ohne Schrecken Ich will diesen thread hier mal ausklingen­ lassen.
Wenn mir was neues zu DCGN einfällt (oder auch zu XOMA),
mache ich was neues auf. Fips17 hatte das hier gestartet,­
ich hab´s dann umgemünzt.­ Wird aber langsam zu lang und unübersich­tlich,


DCGN hat heute abend Zahlen in USA gemeldet, die wohl recht gut
waren. Im Vorfeld zog der Kurs abermals bis weit über 13 Euro an.
Gleichzeit­ig wurde der Kurs in Euro erstmals nach Jahren wieder
zweistelli­g in BRD. Ein lang ersehntes Ziel wurde wahr und ich
habe einen Teil meiner Goldstücke­ verkauft.
Keine Ahnung wie es morgen weiter geht. Ob "sell on good news" greift
oder die Aktie jetzt immer "ernster" genommen wird.
Schön war´s in letzter Zeit.

Wenn doch Börse nur öfter so befriedige­nd wäre!
 
08.10.08 17:23 #84  baanbruch
Weiter geht es in einem anderen Thread
Und zwar dem hier, gestartet von centy01:

http://www­.ariva.de/­DECODE_GEN­ETICS_Rebo­und_t34264­5#jump4807­804

 
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